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Polynucleotides

Discover ACRE’s collection of leading polynucleotides, famed for their incredible regenerative and bio-stimulating properties. Polynucleotides work on a cellular level to hydrate, rejuvenate, and improve skin health from within. Buy polynucleotides from ACRE Pharmacy today.
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Polynucleotide Uses

Derived from purified fish DNA, polynucleotides have bio-stimulating, anti-inflammatory benefits, which stimulate the production of collagen and elastin to treat a wide range of skin concerns, including:

  • Fine lines and periocular wrinkles
  • Loss of elasticity
  • Dull, dehydrated skin
  • Acne scars
  • Hyperpigmentation and sun damage

Buy Trusted Polynucleotides from ACRE Pharmacy

Acre is a UK-based pharmacy registered by the General Pharmaceutical Council (GPhC). Our vast selection of skin-enhancing products, including our polynucleotide injections, skin boosters, dermal fillers, and more are available to approved prescribers only. Registration to order through us can be made through our eRx Manager platform.

POLYNUCLEOTIDE FAQs


What is a Polynucleotide?

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Polynucleotides are naturally occurring fragments of DNA derived from fish that are injected into the skin to trigger a rejuvenating response. The DNA is extracted, then distilled and purified before being added to an injectable gel formula.

How Long Do Polynucleotides Last?

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Polynucleotide treatment offers long-lasting results, with effects typically lasting between six and 12 months.


The duration of the post-treatment effects depends on the patient’s age and the severity of the condition being treated. Older patients may require a maintenance treatment every four to six months. Younger patients usually retain their results for longer, with maintenance treatments recommended around every 12 months.


Patients should be guided individually based on age and overall concerns, as with all aesthetic treatments.


How Long Do Polynucleotides Take to Work?

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Following polynucleotide injections, patients can experience a notable difference in healthier-looking, hydrated skin within one to two weeks. As cellular activity is stimulated to produce collagen and elastin, full results can take up to six weeks to appear.

What is the Best Polynucleotide?

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ACRE supplies a selection of polynucleotides by market-leading brands like Nucleofill and Plinest. The best polynucleotide depends on the area being treated. Some polynucleotide injections, like PolyPhil Hair and Nucleofill Hair, are formulated to be injected in the scalp to reduce hair loss, whilst others are made to be injected into different areas of the face, such as Plinest Eye for the periorbital area or Nucleofill Strong for mature, ageing skin.


What is a Polynucleotide Treatment for the Eyes?

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A polynucleotide treatment for the eyes is a targeting treatment aimed at reducing wrinkles, such as crow’s feet, or reducing the appearance of darkened, hollow under eyes. Once injected in the eye area, polynucleotides trigger cellular regeneration to plump and hydrate the under eyes, giving them a more youthful appearance. There are specific polynucleotide injections for eye treatments, such as PolyPhil Eye or Nucleofill Soft.


What Do Polynucleotide Injections Do?

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Polynucleotides act as bio-stimulators, working on a cellular level to stimulate fibroblast cells, triggering the production of collagen and elastin. These minimally invasive injectables are a great solution for improving skin texture, elasticity, and quality.

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