<img height="1" width="1" style="display:none" src="https://www.facebook.com/tr?id=455570291913660&amp;amp;ev=PageView&amp;amp;noscript=1"> AWvi Pigmentation & Uneven Tone Solutions | ACRE Pharmacy

Skin Discolouration and Pigmentation

Discolouration and pigmentation irregularities are not isolated surface concerns but arise from an interplay of dysregulated melanogenesis, barrier disruption, subclinical inflammation, and oxidative stress. These processes are often amplified by microbiome imbalance, immune reactivity, and impaired epidermal turnover—factors that alter melanin production, distribution, and clearance.


AWvi approaches pigmentation concerns through physiological recalibration rather than pigment suppression. Each solution targets a distinct biological factor—internal or external—contributing to chromatic imbalance. The inside-out and outside-in synergy restores immune and microbial balance, supports cellular repair, and regulates the pathways involved in melanin synthesis and degradation. This biologically anchored approach offers a more sustainable and tolerable alternative to conventional pigment-lightening agents.

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Targeted Mechanisms of Action


The Skin Biotic

CORE ESSENTIAL – Fundamental to restore or maintain physiological skin function.


The Skin Biotic addresses pigmentation at its systemic root by regulating gut microbiota, which influences immune tone and oxidative stress—two critical modulators of melanogenesis. Formulated with three proprietary Lactobacillus strains, prebiotics, and bioavailable Retinol and D-Biotin, it supports internal balance and enhances the skin's regenerative capacity.


Its primary actions include:

  • Modulation of inflammatory mediators that upregulate melanocyte activity
  • Reduction of systemic oxidative stress influencing pigment expression
  • Promotion of epidermal turnover to accelerate pigment dispersion
  • Support of barrier repair and microbial signalling pathways associated with post-inflammatory hyperpigmentation

The Skin Biotic acts upstream of pigmentation, recalibrating immune and metabolic conditions that drive both intrinsic and reactive pigment irregularities.


The Power Serum

CORE ESSENTIAL – Fundamental to restore or maintain physiological skin function.


The Power Serum delivers a blend of broad-spectrum hyaluronic acid, ectoin, and anti-inflammatory actives to support dermal regeneration and pigmentation correction. It targets the skin’s three-dimensional architecture, improving its ability to restore even tone through cellular turnover and controlled repair.


Its effects include:

  • Acceleration of epidermal renewal to reduce pigment persistence
  • Regulation of stress-induced melanogenesis through ectoin
  • Reinforcement of skin defences to prevent pigment recurrence
  • Smoothing of texture and tone by enhancing matrix integrity

Through its deep hydration and repair-promoting properties, the serum creates a favourable environment for progressive, physiologically controlled pigment correction.


The Gentle Cleanser

STRATEGIC SUPPORT – Strongly recommended to enhance outcomes or address key needs.


The Gentle Cleanser ensures the integrity of the microbiome and barrier during cleansing—both critical to managing pigmentation linked to inflammation and barrier compromise. It incorporates ectoin, biomimetic hyaluronic acid, active waters, and non-disruptive surfactants.


Key benefits include:

  • Protection of the skin from inflammation-triggered pigment production
  • Maintenance of a stable barrier and microbial ecology to reduce melanin overexpression
  • Prevention of external irritant-induced post-inflammatory hyperpigmentation
  • Optimal preparation for active absorption and tone-regulating actives

In cases of recurrent or diffuse pigmentation, avoiding barrier damage during cleansing is fundamental. This formulation provides that baseline support.


The Active Cream

TARGETED INTEGRATION – Optional enhancement, to be considered case-by-case.


While not targeted at melanin pathways per se, The Active Cream enhances the skin’s resilience, aiding in the long-term management of uneven tone. Its combination of biomimetic lipids, ectoin, and hyaluronic acid supports hydration, reduces chronic low-grade inflammation, and contributes to post-lesional tone normalisation.


Key mechanisms:

  • Reinforcement of the skin’s barrier to limit pigment-triggering stimuli
  • Support of dermal hydration to improve light reflection and uniformity
  • Downregulation of inflammatory cascades that exacerbate chromatic irregularities
  • Maintenance of cutaneous homeostasis during and after intensive treatments

It serves as an integrative layer in protocols requiring prolonged barrier support or in cases of pigment sensitivity and intolerance to depigmenting agents.


Before & Afters

Pigmentation before and after
Radiance before and after
Skin barrier before and after
Smoothness before and after