Arthrosamid (6 x 1ml)
Arthrosamid® is a single, minimally invasive, long-lasting knee OA treatment — a non-biodegradable injectable polyacrylamide hydrogel (2.5 iPAAG) for intra-articular use. It permanently combines with the tissue lining the knee joint and it’s this unique characteristic that provides a significant reduction in OA pain over a longer period with one single treatment.
Key Features
- the first and only approved 2.5 iPAAG treatment that permanently integrates into the synovial membrane — decreasing joint stiffness, diminishing pain, and improving the function of the knee.
- Clinically proven to maintain a statistically significant reduction in pain in patients with knee OA 4 years after treatment.
- Non-degradable structural stability of hydrogel provides longevity of action.
- Viscoelastic cross-linked chains of polymer allow flexible shear.
- Biocompatible permeable to salts and organic molecules the hydrogel is able to integrate with soft tissue.
Indications
Arthrosamid® is intended to be used for symptomatic treatment of adult patients with knee osteoarthritis.
Composed of 97.5% sterile water and 2.5% cross-linked polyacrylamide.
Box Contents
6 x 1ml
What is polyacrylamide hydrogel?
A polyacrylamide hydrogel is a group of cross-linked polymeric material, which hold large amounts of water while maintaining their structure. They possess a degree of flexibility very similar to natural tissue due to their large water content. Arthrosamid® is a hydrogel. It is an inert, non-pyrogenic polymer gel consisting of 97.5% sterile water and 2.5% cross-linked polyacrylamide and has water exchanging capabilities.
How long does Arthrosamid® last?
The hydrogel making up the injection will not degrade and therefore will provide long-lasting relief. So far, most patients have reported a significant reduction in their pain 4 weeks after their injection, and the average level of reduction was maintained at the 4-year follow-up period.
How does the osteoarthritis inflammatory response get reduced with treatment?
The inflammation response comes most probably from wear and tears, Arthrosamid®, once injected into the area around the inner joint capsule, it restores viscosity within the synovial fluid, improving lubrication. Arthrosamid® integrates into the synovium of the inner joint capsule creating a cushion-like effect.
How does pain get reduced?
The exact way that pain gets turned off is being investigated. Arthrosamid® works to cushion the joint, in clinical trials it can reduce the pain, decrease stiffness, and helps movement. It has been shown to be safe and can give long-acting relief, improving the quality of life.
Can the patient receive Arthrosamid® treatment in both knees?
Yes, it is possible to have both knees injected but the physician is best placed to decide the time period before the treatments.
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