AWvi
About AWvi
AWvi offers a patented, physiology-based approach to skin regulation, acting from the inside out and the outside in. The patent, granted following a formal scientific and technical evaluation, is underpinned by a randomised, double-blind, placebo-controlled clinical study. This approach, validated through peer-reviewed publications, is adopted by leading aesthetic doctors and skin experts.
Combining a targeted nutraceutical with advanced cosmeceuticals, AWvi supports the skin at a systemic level, addressing visible concerns while acting on deeper biological pathways. Central to this approach is the gut–skin axis, through which AWvi supports skin physiology from within, while dermocosmetic formulations support skin biophysical parameters. AWvi’s solutions reinforce barrier integrity, regulate inflammation, and activate internal processes involved in repair and cellular homeostasis, supporting the skin’s physiological processes of protection, adaptation, and regeneration.
This is achieved in particular by its microbiome-centred mechanism of action, enabling the delivery of clinically proven benefits across multiple dimensions of skin health through microbial modulation, as an imbalanced microbiome, whether intestinal or cutaneous, disrupts key physiological processes involved in skin homeostasis, contributing to barrier dysfunction, chronic inflammation, and heightened skin reactivity.
In partnership with ACRE, AWvi provides practitioners with solutions that can be used individually or in combination, and that integrate seamlessly alongside other aesthetic or clinical treatments to optimise and prolong outcomes by acting at a different level of the skin ecosystem across a wide range of patient profiles, addressing concerns ranging from dryness and signs of ageing to sensitivity, acne-prone and redness-prone skin, as well as chronic inflammatory conditions such as rosacea, dermatitis, and eczema.
A multilayered, microbiome-centred approach to systemic skin optimisation
AWvi’s solutions operate across interconnected biological layers, targeting both the gut and the skin to restore balance, regulate inflammation, and support repair.
In the gut lumen, the nutraceutical modulates microbial diversity and metabolite production, strengthening the mucosal barrier, lowering systemic inflammatory signalling, and promoting beneficial postbiotic activity.
Across the intestinal barrier, improved epithelial integrity and immune modulation reduce systemic inflammatory burden, enhancing the skin’s capacity to adapt and regenerate.
Within systemic circulation, cytokine balance and oxidative stress buffering contribute to improved extracellular matrix function and dermal homeostasis.
At the skin level, each AWvi cosmeceutical fulfils a distinct physiological function, yet all are formulated around a common core of biomimetic actives, developed and adapted in specification to serve the targeted role of each solution:
Ectoin, a biotech-derived molecule with postbiotic properties, supports microbiome resilience by stabilising cell membranes, buffering stress responses, and modulating skin microbial ecology.
Broad-spectrum sodium hyaluronate, spanning a range of molecular weights, delivers hydration across all cutaneous layers: low molecular weights support dermal hydration and cellular signalling, while high molecular weights form a protective film to reduce trans-epidermal water loss and reinforce barrier function.
Biomimetic lipids, including medical-grade triglycerides, restore the skin’s lipid architecture and structural cohesion, reinforcing its capacity for defence and repair.
The combined in-and-out approach has been shown to synergistically enhance the effects of either the supplement or topical formulations by a factor of 2.1, on average, offering superior outcomes in hydration, barrier function, and inflammation regulation through coordinated, layered biological action.
Shop by Skin Type
Each skin type reflects a distinct physiological balance shaped by hydration, barrier integrity, sebum dynamics and microbiome composition. AWvi supports these mechanisms through integrated, science-driven systems that reinforce stability, regulate immune activity and strengthen long-term resilience.
Shop by Skin Concern
Every skin concern stems from specific biological disruptions—whether linked to inflammation, barrier weakness, hydration deficits or uneven renewal. AWvi addresses these mechanisms at their source, offering targeted, science-based solutions that restore balance, optimise regeneration and support sustained skin health.
