The Journal
Written by: ACRE | Published On: February 05, 2026
AWvi: Where beauty meets skin health and longevity
Human skin evolved to function within stable biological rhythms. Modern environmental and lifestyle stressors now place unprecedented demands on its protective and regulatory systems.
AWvi addresses this challenge through a clinically structured approach comprising four complementary solutions. Each formula is designed to support a foundational aspect of skin physiology: microbiome resilience, immune modulation, barrier integrity, and cellular renewal.
Formulated for flexibility, AWvi products may be used independently or combined to create protocols tailored to individual skin types and concerns; supporting the skin’s ability to restore balance, strengthen defences, and adapt to ongoing stress.
What is AWvi's approach?
Skincare is moving beyond surface correction. AWvi focuses on regenerative biology, supporting the skin’s energy, structure, immune balance, and barrier function. This approach recognises that lasting skin health comes from internal systems working together, rather than treating isolated symptoms.
Microbiome: Key drivers of skin function
The microbiome sits at the crossroads of immunity, inflammation, and regeneration. When balanced, it preserves barrier integrity, regulates pigmentation, supports hydration and repair, and buffers the skin against environmental and emotional stress. When disrupted by modern lifestyles, pollution, poor sleep, diet, or aggressive routines, skin resilience breaks down. For AWvi, supporting the microbiome is not an add-on. It is the entry point to regenerative skin care.
AWvi’s microbiome-centred approach integrates prebiotic, probiotic, and postbiotic strategies, each playing a distinct biological role.
Selected prebiotics help support the growth and stability of beneficial microbial communities in the gut, providing further vitality to AWvi’s proprietary probiotic strains (characterised by their specific DNA sequence), which support skin health through the gut–skin axis.
At the topical level, a biotech-derived, stable postbiotic molecule provides bioactive signals that can influence barrier function, immune modulation, and recovery. Together, these mechanisms work in synergy to help create the conditions for a resilient and adaptive skin ecosystem.
What is the ‘In and Out’ strategy?
AWvi’s patented in and out approach combines targeted nutraceuticals and next-gen cosmeceuticals to act across the gut–skin axis, barrier function, immune regulation, and cellular energy production. Clinical data show this combination delivers significantly greater results than either approach alone, enhancing outcomes, improving recovery, and extending the benefits of any aesthetic or dermatological treatments.
What this means for your clients
AWvi’s microbiome-centred approach supports skin health at it’s foundation by nurturing the balance of beneficial bacteria on the skin’s surface, rather than simply treating visible symptoms. By using targeted prebiotics to strengthen the skin barrier and encourage a resilient, diverse microbiome, AWvi products help to reduce inflammation, sensitivity, and moisture loss over time. This makes their protocols effective for clients prone to redness, irritation, or compromised skin barriers. For those searching for the best prebiotic skincare for sensitive skin, this science-led approach offers long-term protection, and more consistent results, allowing the skin to restore and maintain its natural equilibrium.
A biologically coherent system
Each AWvi solution is designed as part of a modular yet synergistic system:
The Skin Biotic
Reconditions skin health from within via the gut–skin axis
The Gentle Cleanser
Preserves pH, microbiome balance, and barrier integrity
The Power Serum
Supports dermal regeneration and mitochondrial resilience
The Active Cream
Maintains long-term hydration, defence, and homeostasis
Together, they activate the logic of living skin, supporting resilience, regeneration, and longevity.
AWvi isn’t a cosmetic routine, it’s a biology-led strategy for skin that works with the body.
AWvi Results
By aligning with skin biology, AWvi supports more consistent and durable outcomes. Clinical data show a 2.1-fold increase in efficacy when an integrated in and out approach combining oral solutions with one or more topical formulations is used, compared with oral or topical solutions alone.
Users typically see improved hydration, reduced redness and sensitivity, faster recovery, and greater overall skin resilience over time.
Frequently Asked Questions
What does “biology-led skin care” mean?
Biology-led skin care focuses on how skin functions rather than how it looks in isolation. Instead of treating symptoms alone, it supports the underlying biological systems, such as the microbiome, immune regulation, barrier integrity, and cellular energy, that determine skin resilience, repair, and long-term health.
Why is the microbiome so important for skin health?
The microbiome regulates inflammation, immune tolerance, hydration, pigmentation, and barrier function. When balanced, it helps skin remain resilient and adaptable. When disrupted, it contributes to sensitivity, inflammation, pigmentary disorders, delayed healing, and accelerated ageing. Supporting the microbiome is therefore foundational, not optional.
What does “In and Out” mean?
“In and Out” refers to combining oral (nutraceutical) and topical (cosmeceutical) solutions. Skin health is regulated both systemically and locally. Addressing only one side limits results, while combining both creates a synergistic effect across the gut–skin axis, immune pathways, and barrier repair.
Can AWvi be used alongside aesthetic or dermatological treatments?
Yes. AWvi is designed to complement clinical treatments and aesthetic procedures. By improving tissue quality, barrier resilience, and inflammatory control, it can enhance results, support recovery, reduce downtime, and help maintain outcomes over time.
Do I need to use all AWvi products together?
Each product is effective on its own, while the system is designed to operate synergistically through structured protocols. The in and out approach can be tailored according to individual skin types, concerns, or goals, enabling more consistent and durable outcomes by engaging multiple biological pathways in a coordinated manner.
Why buy products from ACRE
Choose ACRE for complete peace of mind. Our inventory boasts a diverse selection of trusted aesthetic supplies, including skin boosters, dermal fillers, and polynucleotides. We prioritise patient safety, consistently securing reliable products from regulated suppliers, including essential consumables to fully equip your clinic for all treatments.
