The Journal
Written by: Hannah Lee | Published On: June 05, 2025
The Best Anti-Wrinkle Injections: A Brand Comparison
As non-surgical aesthetic treatments continue to grow in popularity, clients are becoming more informed and selective about the products being used on them. It’s important for practitioners to stay up to date on the best brand of Botox available to deliver safe, effective results.
But with so many options available on the market, what is the best Botox brand to choose for your clinic? Our guide will help you determine the best Botox brand for face treatments, factoring in longevity and efficacy.
What is Botox?
Toxins and diluents, also known as antiwrinkle injections or commonly referred to as Botox, are botulinum injections used to smooth out the look of dynamic wrinkles such as frown lines, crow’s feet, and forehead lines by relaxing the facial muscles.
Injecting toxins into the muscle prevents the release of acetylcholine, blocking nerve signals to the muscles and causing them to relax. This can make the skin appear smoother and tighter for a more youthful appearance.
Treatment Considerations
Although anti-wrinkle injections are a non-surgical way of achieving similar results as a facelift, practitioners should take some considerations into account. It’s vital to conduct a pre-treatment consultation to ensure the client’s suitability before proceeding with the procedure–discuss any medical conditions, medication, or allergies the client may have.
A post-treatment consultation must also be conducted to inform the client about how best to take care of themselves during the healing process.
What is the Best Botox Brand?
ACRE Pharmacy stocks a wide range of market-leading antiwrinkle injection brands, such as Botox, Azzalure, Dysport, and more. The main difference between these brands is their formulation, namely the type of botulinum toxin used, which can influence diffusion, onset time, client tolerance, and duration of results.
Here’s a breakdown of the brands we offer, including the type of toxin they use, where they’re best injected for optimal results, longevity, and estimated costs, to help you choose the best Botox brand for your clinic.
Azzalure
Azzalure is a popular botulinum type A toxin injection, as it is an effective option for improving the appearance of fine lines and wrinkles. It’s recommended for adults under 65 and can smooth out the look of glabellar lines and lateral canthal lines.
It’s generally fast-acting with broader diffusion, making it ideal for larger treatment areas. Azzalure’s onset time is around two to three days, with results lasting up to six months.
Alluzience
Alluzience is a liquid botulinum type A toxin injection, and the first ready-to-use neuromodulator in Europe. The liquid formulation eliminates the need for reconstitution, making a convenient and fast-acting solution for forehead and glabellar lines.
Results can take two to three days to appear, and last up to six months.
Bocouture
Bocouture is a botulinum type A neurotoxin injection that can be used for various medical and cosmetic purposes. It reduces the appearance of dynamic wrinkles, such as forehead and glabellar lines and crow’s feet. Bocouture is best used for patients concerned about long-term resistance, as its expert formulation reduces the potential of antibody development.
It usually takes two to three days for Bocouture to start to take effect, with the results in visible wrinkles and line reduction becoming noticeable after around ten days. The results usually last between three and four months.
Botox
Botox is largely recognised as the industry benchmark, which is why anti-wrinkle injections are commonly referred to as ‘Botox injections’, no matter the brand used. This botulinum type A toxin injection is a top choice amongst medical professionals, both for cosmetic and medical treatment. It temporarily reduces wrinkles and fine lines and boasts therapeutic benefits, such as treating migraines, muscle spasms, and excessive sweating.
The onset time takes around three to five days, with results lasting between three and four months.
Dysport
Dysport is another great Botulinum type A toxin injection used to prevent muscle contraction and soften dynamic wrinkles. It’s a cost-effective option for larger treatment areas due to its fast onset and broader diffusion. However, this means that a precise injection technique is required to avoid spreading into unwanted areas.
The onset time is usually fast but can take between two and three days, with results lasting up to four months.
Letybo
Letybo is a newer botulinum type A toxin in the UK, which has grown in popularity due to its clean formulation and efficacy. Outside of cosmetic use, it can address muscular conditions such as Bruxism, chronic migraines, or excessive sweating.
It is suitable for clients under 75 who want to reduce fine lines and wrinkles in the forehead and glabellar areas. Results can take two to four days to appear and last up to four months.
Relfydress
Relfydess™ (RelabotulinumtoxinA) is the first and only ready-to-use liquid neuromodulator created with PEARL™ Technology. Its clean formulation is used to reduce the appearance of mild to moderate facial wrinkles. It’s a budget-friendly option for clinics wanting to provide affordable anti-wrinkle treatments.
It has an onset of three to five days, with results lasting up to four months.
Discover ACRE’s Line of Toxins and Diluents
Choosing the best brand of Botox for your clinic ultimately depends on your client’s treatment goals, medical history, and your preferred injection techniques. Whether you're seeking rapid onset, longer duration, or options with reduced protein load to lower resistance risk, ACRE Pharmacy offers every major brand trusted by aesthetic professionals.
Explore our full range of toxins and diluents, as well as different facial rejuvenating solutions, such as dermal fillers and skin boosters. For any further information about our products, please contact us.
