The Journal
Written by: ACRE | Published On: January 13, 2026
What is Ozempic Face and How Can it Be Treated?
‘Ozempic face’ is a term used to describe facial volume loss linked to GLP-1 weight-loss injections such as Ozempic and Wegovy. In this guide, we’ll break down what Ozempic Face really is, how to avoid it during weight loss, and the best aesthetic treatments available.
Weight loss injections have quickly risen in popularity over the last few years, deemed miracle solutions for weight management. While they can be effective for those looking to lose a few pounds, rapid weight loss can transform your body, and for some, it also changes the face.
What is Ozempic Face?
Ozempic face refers to facial changes that occur after rapid or significant weight loss, particularly in people using GLP-1 medications like Ozempic.
Ozempic face is not a medical condition but a visible side effect of fat loss in the face. It is caused by the skin and body being unable to adapt quickly enough to fast weight loss, leading to loss of subcutaneous fat and elasticity and reduced collagen. Common signs of Ozempic face can include:
- Hollow cheeks and temples
- Sunken under eyes
- Wrinkles and increased skin laxity
- Tired or aged appearance
How to Avoid Ozempic Face During Weight Loss?
While Ozempic Face isn’t always preventable, the risk can be significantly reduced with the right approach.
- Lose weight gradually where clinically appropriate: Discuss lower medication dosages with your doctor; all GLP-1 agonists, such as Ozempic, are to be titrated under the careful supervision of your doctor to avoid rapid and unstable weight loss.
- Avoid excessive calorie restriction alongside GLP-1 therapy: Following a balanced diet and exercising regularly (if recommended by your doctor), alongside using weight loss medication, ensures gradual, longer-lasting results
- Maintain adequate protein intake to support collagen
- Stay hydrated to preserve skin elasticity
- Introduce skin treatments early, rather than waiting for volume loss
It’s better to prioritise early prevention rather than trying to reverse Ozempic face after the fact. Supporting skin quality and collagen production during weight loss can help prevent long-term facial changes.
The Best Treatment for Ozempic Face
Dermal Fillers
Dermal fillers are an effective, non-surgical way of combating signs of ageing and an excellent solution for treating Ozempic face. They’re designed to restore lost volume in sunken areas, plump out wrinkles and folds, and also hydrate the skin. Fillers are commonly used in the cheeks, temples, jawline, and under-eye area to rebalance facial proportions after weight loss.
Benefits for Ozempic face:
- Restores lost facial volume
- Improves facial contours
- Provides immediate visible results
Biostimulators
Biostimulators, like polynucleotides and PLLAs, such as Sculptra, are advanced injectable treatments designed to repair and regenerate skin at a cellular level. Unlike dermal fillers, biostimulators work at the cellular level to stimulate collagen and elastin production, promoting cell turnover.
Benefits for Ozempic face:
- Improves skin elasticity and firmness
- Stimulates collagen production
- Enhances hydration and skin quality
- Delivers natural, gradual rejuvenation
Skin-Tightening Treatments
Skin-tightening treatments provide another minimally invasive solution for improving skin laxity rather than volume loss. This is a better option for patients with tamer side effects of Ozempic face looking to rejuvenate their appearance.
High-intensity focused ultrasound (HIFU), which uses ultrasound energy to promote collagen production; RF microneedling, which combines radiofrequency energy with microneedling to rejuvenate and tighten the skin; and laser resurfacing, which uses a laser to remove damaged outer layers of skin and stimulate the growth of new, healthy skin.
Benefits for Ozempic face:
- Stimulate collagen and elastin
- Improve firmness and texture
- Works well alongside fillers and polynucleotides
FAQs: Common Patient Questions
Is Ozempic face permanent?
No, Ozempic face is treatable and often reversible with the right approach, especially when addressed early.
What’s the best treatment for Ozempic face?
The best treatment depends on the individual, but a combination of dermal fillers and polynucleotides is widely considered the gold standard for restoring volume and improving skin quality naturally.
How common is Ozempic face?
Not all patients experience facial volume loss; it depends on several factors, including age, genetics, rate of weight loss, and skin quality.
Shop ACRE Pharmacy’s Range of Ozempic Face Treatments
Dermal fillers and biostimulating injectables are not a standalone cure for facial volume loss, but they play an essential role in improving hydration, elasticity, and overall skin quality. When combined with skin-tightening treatments, they can dramatically improve the appearance of Ozempic Face.
Discover ACRE Pharmacy’s range of CE-marked, industry-leading injectables. As a trusted UK-based pharmacy, registered with the General Pharmaceutical Council, we supply professionals with market-leading aesthetic products. Order online today or contact us for further information.
